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JANKOWSKY, JOANNA

One or more keywords matched the following items that are connected to JANKOWSKY, JOANNA

Item Type	Name
Academic Article	Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase.
Academic Article	Environmental enrichment exacerbates amyloid plaque formation in a transgenic mouse model of Alzheimer disease.
Academic Article	APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1.
Academic Article	Transgenic mouse models of neurodegenerative disease: opportunities for therapeutic development.
Academic Article	Remote sites of structural atrophy predict later amyloid formation in a mouse model of Alzheimer's disease.
Academic Article	Transgenic APP expression during postnatal development causes persistent locomotor hyperactivity in the adult.
Academic Article	Robust amyloid clearance in a mouse model of Alzheimer's disease provides novel insights into the mechanism of amyloid-beta immunotherapy.
Academic Article	Environmental enrichment mitigates cognitive deficits in a mouse model of Alzheimer's disease.
Academic Article	Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease.
Academic Article	Alzheimer's-type amyloidosis in transgenic mice impairs survival of newborn neurons derived from adult hippocampal neurogenesis.
Concept	Alzheimer Disease
Academic Article	Genetic suppression of transgenic APP rescues Hypersynchronous network activity in a mouse model of Alzeimer's disease.
Academic Article	Genetic modulation of soluble A? rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease.
Academic Article	Impairments in experience-dependent scaling and stability of hippocampal place fields limit spatial learning in a mouse model of Alzheimer's disease.
Academic Article	NF?B-activated astroglial release of complement C3 compromises neuronal morphology and function associated with Alzheimer's disease.
Academic Article	Quaternary Structure Defines a Large Class of Amyloid-? Oligomers Neutralized by Sequestration.
Academic Article	Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease.
Academic Article	Amyloid-? plaques disrupt axon initial segments.
Academic Article	Practical considerations for choosing a mouse model of Alzheimer's disease.
Academic Article	Combination of A? Suppression and Innate Immune Activation in the Brain Significantly Attenuates Amyloid Plaque Deposition.
Academic Article	Discrete Pools of Oligomeric Amyloid-? Track with Spatial Learning Deficits in a Mouse Model of Alzheimer Amyloidosis.
Academic Article	Combination anti-A? treatment maximizes cognitive recovery and rebalances mTOR signaling in APP mice.
Academic Article	Cross-species genetic screens to identify kinase targets for APP reduction in Alzheimer's disease.
Grant	Deconstructing the pathogenic effect of APP in memory circuits
Grant	Interaction of ABeta &the alpha7 AChR in mouse AD model
Grant	Interrogating the link between aging and AD with temporally-controlled transgenes
Grant	Selective neuronal silencing to study cognitive decline in Alzheimer's disease
Grant	Distinguishing cell-intrinsic and cell-extrinsic effects of APP/Abeta in vivo
Academic Article	Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease.
Academic Article	Gene therapy using A? variants for amyloid reduction.
Grant	Gene therapy for Alzheimer's disease using virally delivered Aß variants
Grant	Decoding the impact of sex differences on Alzheimer's disease risk

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Alzheimer Disease